C-REACTIVE PROTEIN

22 DECEMBER 2020

C-reactive protein levels increase in response to inflammation. It is for this reason that it is grouped within the so-called acute phase proteins.

Identifying them is very important and helps health professionals take decisions in a wide range of fields. Some of them are critical, such as assessing the evolution of a systemic infection in a newborn patient, assessing the risk of heart attack, or to control the spread of COVID-19. During its early years, Spinreact focused its efforts on develop chemical reagents. We were still in the early stages of in-vitro diagnostics. In just a short time, in the early 80s, they started using the first enzymes and before 1990, a product based on the antigen-antibody binding was added to the Spinreact catalogue for the first time. This is how the PCR-latex reagent was born.

This method, which is currently used broadly, makes it possible to visually identify the C-reactive protein by agglutination. It is enough to mix a drop of the PCR-latex reagent with a drop of serum to have an accurate idea of the number of PCR in the sample.

In time, photometers started to be implemented and gradually they incorporated the ability to read turbidimetry. This opened up the possibility of determining a series of proteins quantitatively. Using this new technology, in the mid 90s, Spinreact launched its PCR-Turbilatex method, which could accurately measure the concentration of the C-reactive protein in blood. Both products were very successful. In just a few years, PCR testing was Spinreact's best-selling technique. Both in terms of volume and turnover. This trend continues to this day. Though it is true that the quantitative method is currently ahead, the number of PCR-latex (manual) kits sold is very significant. Spinreact has established itself as one of the leading PCR manufacturers in the world year after year. Our methods to determine the C-reactive protein are currently used in over 120 countries and the number of daily determinations made with our products is almost too much to count. We calculate that every second 6 samples are analysed for PCR using a Spinreact reagent.

  • ☑  Every second, 5 people around the world can know their PCR level thanks to Spinreact

22 DECEMBER 2020

C-reactive protein levels increase in response to inflammation. It is for this reason that it is grouped within the so-called acute phase proteins.

Identifying them is very important and helps health professionals take decisions in a wide range of fields. Some of them are critical, such as assessing the evolution of a systemic infection in a newborn patient, assessing the risk of heart attack, or to control the spread of COVID-19. During its early years, Spinreact focused its efforts on develop chemical reagents. We were still in the early stages of in-vitro diagnostics. In just a short time, in the early 80s, they started using the first enzymes and before 1990, a product based on the antigen-antibody binding was added to the Spinreact catalogue for the first time. This is how the PCR-latex reagent was born.

This method, which is currently used broadly, makes it possible to visually identify the C-reactive protein by agglutination. It is enough to mix a drop of the PCR-latex reagent with a drop of serum to have an accurate idea of the number of PCR in the sample.

In time, photometers started to be implemented and gradually they incorporated the ability to read turbidimetry. This opened up the possibility of determining a series of proteins quantitatively. Using this new technology, in the mid 90s, Spinreact launched its PCR-Turbilatex method, which could accurately measure the concentration of the C-reactive protein in blood. Both products were very successful. In just a few years, PCR testing was Spinreact's best-selling technique. Both in terms of volume and turnover. This trend continues to this day. Though it is true that the quantitative method is currently ahead, the number of PCR-latex (manual) kits sold is very significant. Spinreact has established itself as one of the leading PCR manufacturers in the world year after year. Our methods to determine the C-reactive protein are currently used in over 120 countries and the number of daily determinations made with our products is almost too much to count. We calculate that every second 6 samples are analysed for PCR using a Spinreact reagent.

  • •  Every second, 5 people around the world can know their PCR level thanks to Spinreact

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